In the game at Heinz Field, the Patriots faced off against the Pittsburgh Steelers, who started their backup QB Landry Jones as their regular starter, Ben Roethlisberger, was out with a knee injury.
After a Steelers three-and-out, on the Patriots first offensive play, Brady hit Chris Hogan for a 12-yard gain, but Hogan was stripped by Jarvis Jones, who recovered the ball at the Patriots 45. The Steelers drove to the Patriots 16, but on 3rd-and-6, Landry Jones was intercepted in the end zone by Malcolm Butler on a pass intended for Antonio Brown. Taking over at their own 20, the Patriots went on an 80 yard marathon, taking 13 plays, with Brady finding James White on a 19-yard touchdown pass. After the Steelers went three-and-out again, the Patriots marched 84 more yards, scoring on Blount's 3-yard touchdown four minutes into the second quarter, increasing the Patriots lead to 14-0. The Steelers countered on their next drive. Aided by Brown's 51-yard catch, they trimmed the score to 14-7 on a 14-yard touchdown catch by Darrius Heyward-Bey. After a Patriot three-and-out, a bad punt byRyan Allen gave the Steelers the ball at the Steelers 47. Six plays later, Jones hit Heyward-Bey for a 14-yard touchdown, but the play was nullified for a holding penalty on Chris Hubbard. On the next play Jones threw an incompletion and Chris Boswell missed a 42-yard field goal. The Patriots reached midfield on their next drive, but were forced to punt. Allen pinned the Steelers at their own 6, but the Steelers challenged that the ball hit the end zone, and the ruling was reversed giving the Steelers the ball at the 20. With the better field position, the Steelers drove 66 yards to the Patriots 14, and Boswell was good from 32 yards and the score was 14-10 Patriots at halftime.
After a Patriots three-and-out, the Steelers drove to the Patriots 28 and Boswell made a 46-yard field goal, trimming the score to just 14-13. The Patriots countered, through, racing 75 yards in a mere 5 plays and Brady threw a 36-yard laser to Gronkowski for a touchdown, increasing the lead to 20-13, but Gostkowski missed his second extra point of the season. Justin Gilbert returned the ensuing kickoff 32 yards to the Steelers 42. Aided by the pretty good field position, Pittsburgh responded by driving 42 yards to the Patriots 26, and Boswell kicked a 44-yard field goal trimming the score to 20-16 on the third play of the fourth quarter. The Patriots countered again, racing 75 yards and Blount scored on a 5-yard touchdown run, increasing the lead to 27-16. The Steelers were forced to punt on their next drive, but Edelman fumbled and the Steelers recovered at the Patriots 43. The Steelers reached the 36, but Boswell missed a 54-yard field goal, keeping the Patriots ahead 27-16. Later in the fourth quarter, the Steelers drove to the Patriots 45, but turned the ball over on downs after Jones threw an incomplete pass on 4th-and-11. Brady took a knee and the Patriots won the game.
With the win the Patriots improved to 6–1 and 3-0 under Brady.